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polyclonal rabbit anti human leptin ab  (BioVendor Instruments)


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    Structured Review

    BioVendor Instruments polyclonal rabbit anti human leptin ab
    <t>Leptin</t> depletion or neutralization inhibits <t>polyclonal</t> T cell proliferation and mixed lymphocyte reactions (MLR), respectively. (a–c)The proliferative response of T lymphocytes to polyclonal stimuli (OKT3, PHA, and PMA/Iono) from controls is completely inhibited in medium with human serum depleted of leptin. Addition of recombinant human leptin (at 100 ng/ml final concentration) completely reverses this phenomenon. (d) Anti-leptin blocking Abs partially inhibit the antigen-specific proliferative response of T cells during MLR. HS, human serum.
    Polyclonal Rabbit Anti Human Leptin Ab, supplied by BioVendor Instruments, used in various techniques. Bioz Stars score: 92/100, based on 8 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/polyclonal rabbit anti human leptin ab/product/BioVendor Instruments
    Average 92 stars, based on 8 article reviews
    polyclonal rabbit anti human leptin ab - by Bioz Stars, 2026-03
    92/100 stars

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    1) Product Images from "Differential regulation of metabolic, neuroendocrine, and immune function by leptin in humans"

    Article Title: Differential regulation of metabolic, neuroendocrine, and immune function by leptin in humans

    Journal:

    doi: 10.1073/pnas.0505429103

    Leptin depletion or neutralization inhibits polyclonal T cell proliferation and mixed lymphocyte reactions (MLR), respectively. (a–c)The proliferative response of T lymphocytes to polyclonal stimuli (OKT3, PHA, and PMA/Iono) from controls is completely inhibited in medium with human serum depleted of leptin. Addition of recombinant human leptin (at 100 ng/ml final concentration) completely reverses this phenomenon. (d) Anti-leptin blocking Abs partially inhibit the antigen-specific proliferative response of T cells during MLR. HS, human serum.
    Figure Legend Snippet: Leptin depletion or neutralization inhibits polyclonal T cell proliferation and mixed lymphocyte reactions (MLR), respectively. (a–c)The proliferative response of T lymphocytes to polyclonal stimuli (OKT3, PHA, and PMA/Iono) from controls is completely inhibited in medium with human serum depleted of leptin. Addition of recombinant human leptin (at 100 ng/ml final concentration) completely reverses this phenomenon. (d) Anti-leptin blocking Abs partially inhibit the antigen-specific proliferative response of T cells during MLR. HS, human serum.

    Techniques Used: Neutralization, Recombinant, Concentration Assay, Blocking Assay



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    92
    BioVendor Instruments polyclonal rabbit anti human leptin ab
    <t>Leptin</t> depletion or neutralization inhibits <t>polyclonal</t> T cell proliferation and mixed lymphocyte reactions (MLR), respectively. (a–c)The proliferative response of T lymphocytes to polyclonal stimuli (OKT3, PHA, and PMA/Iono) from controls is completely inhibited in medium with human serum depleted of leptin. Addition of recombinant human leptin (at 100 ng/ml final concentration) completely reverses this phenomenon. (d) Anti-leptin blocking Abs partially inhibit the antigen-specific proliferative response of T cells during MLR. HS, human serum.
    Polyclonal Rabbit Anti Human Leptin Ab, supplied by BioVendor Instruments, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/polyclonal rabbit anti human leptin ab/product/BioVendor Instruments
    Average 92 stars, based on 1 article reviews
    polyclonal rabbit anti human leptin ab - by Bioz Stars, 2026-03
    92/100 stars
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    Leptin depletion or neutralization inhibits polyclonal T cell proliferation and mixed lymphocyte reactions (MLR), respectively. (a–c)The proliferative response of T lymphocytes to polyclonal stimuli (OKT3, PHA, and PMA/Iono) from controls is completely inhibited in medium with human serum depleted of leptin. Addition of recombinant human leptin (at 100 ng/ml final concentration) completely reverses this phenomenon. (d) Anti-leptin blocking Abs partially inhibit the antigen-specific proliferative response of T cells during MLR. HS, human serum.

    Journal:

    Article Title: Differential regulation of metabolic, neuroendocrine, and immune function by leptin in humans

    doi: 10.1073/pnas.0505429103

    Figure Lengend Snippet: Leptin depletion or neutralization inhibits polyclonal T cell proliferation and mixed lymphocyte reactions (MLR), respectively. (a–c)The proliferative response of T lymphocytes to polyclonal stimuli (OKT3, PHA, and PMA/Iono) from controls is completely inhibited in medium with human serum depleted of leptin. Addition of recombinant human leptin (at 100 ng/ml final concentration) completely reverses this phenomenon. (d) Anti-leptin blocking Abs partially inhibit the antigen-specific proliferative response of T cells during MLR. HS, human serum.

    Article Snippet: For leptin depletion from serum, a protein G-Sepharose affinity column (Amersham Pharmacia) was used after adhesion on G protein of a polyclonal rabbit anti-human leptin Ab (BioVendor).

    Techniques: Neutralization, Recombinant, Concentration Assay, Blocking Assay